Opportunity Information: Apply for CDC RFA GH20 2036
This CDC cooperative agreement opportunity (CDC RFA GH20-2036) supports headquarters-led work under PEPFAR to strengthen the digital and informatics backbone needed to reach HIV and TB epidemic control goals. It is framed around PEPFAR 3.0, which prioritizes measurable impact, transparency, and accountability in line with the UNAIDS 95-95-95 targets (diagnose 95 percent of people living with HIV, treat 95 percent of those diagnosed, and achieve viral suppression for 95 percent of those on treatment). The core idea is that countries cannot reliably track progress toward these targets or improve program performance without stronger, more connected health information systems and the policy and workforce structures that sustain them.
The funding is structured as a cooperative agreement, meaning CDC expects substantial involvement in the work rather than simply providing a pass-through grant. For Year 1, CDC anticipated approximately $20,000,000 total funding (subject to availability) and expected to make 2 awards. A notable detail is that the posted Year 1 award ceiling is listed as $0, which typically signals that CDC is not setting a per-award maximum in the announcement (rather than implying there is no funding). The opportunity was open to unrestricted applicants (any entity type, subject to any additional eligibility clarifications in the full notice). The posting indicates an original closing date of February 21, 2020, with electronic submissions due by 11:59 p.m. Eastern Time.
Programmatically, the opportunity emphasizes that eHealth and digital health are foundational to achieving PEPFAR goals because HIV and TB programs generate large volumes of patient-level and site-level data that must be secure, timely, and usable for real-world decision-making. The work centers on four main areas. First, it supports the design, development, implementation, evaluation, and practical use of secure, standards-based, interoperable health information systems (HIS). Interoperability and standards are highlighted because countries often have multiple disconnected systems across clinics, laboratories, pharmacies, and national reporting platforms, and these gaps make it difficult to follow a patient through testing, treatment, and outcomes such as viral suppression.
Second, the opportunity supports the development, implementation, evaluation, and/or adoption of country eHealth or digital health strategies, along with the governance and policy environment that makes those strategies workable. This includes the kinds of national rules and coordination mechanisms that determine how systems are approved, how data are shared, how privacy and security are handled, what technical standards are used, and how different stakeholders (ministries, implementing partners, and donors) align their investments instead of building duplicative tools.
Third, it prioritizes building indigenous health informatics capacity, meaning strengthening the local workforce and institutions that can maintain and improve these systems over time. The intent is to reduce long-term dependence on external technical assistance by developing in-country expertise in informatics leadership, system administration, data standards, interoperability architecture, analytics, and the operational realities of running digital systems in public health settings.
Fourth, it includes monitoring and evaluation (M and E) of HIS implementation itself. This goes beyond measuring HIV or TB outcomes and focuses on whether the information systems are functioning as intended: whether facilities use them consistently, whether data quality is improving, whether interoperability is delivering complete patient histories, whether reporting is timely, and whether the systems actually support better program decisions and performance improvement.
A recurring theme is the need for ongoing support in governance, interoperability, and workforce capacity because countries are increasingly expected to optimize core program operations using routine data. The announcement specifically notes use cases like improving supply chain logistics (so commodities and medications are available where needed), optimizing laboratory utilization (so testing capacity and results reporting support treatment decisions), and improving human resources for health staffing allocation based on site-level program data. By linking disparate systems and improving data flow, countries can more accurately track 95-95-95 progress, identify gaps by geography or population, and protect prior PEPFAR investments in digital infrastructure by ensuring systems are sustainable, secure, and fit for purpose.Apply for CDC RFA GH20 2036
- The Department of Health and Human Services, Centers for Disease Control - CGH in the health sector is offering a public funding opportunity titled "HQ Supported Development, Implementation, Use and Evaluation of Interoperable Health Information Systems to Achieve HIV/AIDS and TB Epidemic Control through Improved Health Informatics Policy, Governance, Workforce Capacity, and Systems under PEPFAR" and is now available to receive applicants.
- Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.067.
- This funding opportunity was created on Dec 22, 2019.
- Applicants must submit their applications by Feb 21, 2020 Electronically submitted applications must be submitted no later than 1159 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
- The number of recipients for this funding is limited to 2 candidate(s).
- Eligible applicants include: Unrestricted (i.e., open to any type of entity above), subject to any clarification in text field entitled Additional Information on Eligibility.
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Frequently Asked Questions (FAQs) - CDC RFA GH20-2036 (PEPFAR Digital Health and Informatics Backbone)
1) What is CDC RFA GH20-2036?
CDC RFA GH20-2036 is a CDC cooperative agreement opportunity that supports headquarters-led work under PEPFAR to strengthen the digital and informatics backbone needed to reach HIV and TB epidemic control goals.
2) What is the main purpose of this opportunity?
The purpose is to help countries improve their ability to reliably track progress toward HIV and TB goals and improve program performance by strengthening connected, secure, and usable health information systems, along with the governance, policy, and workforce structures needed to sustain them.
3) How does this opportunity align with PEPFAR 3.0?
The opportunity is framed around PEPFAR 3.0 priorities, which emphasize measurable impact, transparency, and accountability. It is designed to support progress tracking and performance improvement using routine data.
4) How does the opportunity relate to the UNAIDS 95-95-95 targets?
The work supports countries in tracking and improving performance toward the UNAIDS 95-95-95 targets: diagnosing 95 percent of people living with HIV, treating 95 percent of those diagnosed, and achieving viral suppression for 95 percent of those on treatment.
5) What type of funding mechanism is this?
This is a cooperative agreement, which means CDC expects substantial involvement in the work rather than providing funding with minimal ongoing participation.
6) What does "substantial involvement" mean in this context?
Based on the announcement description of a cooperative agreement, it means CDC is expected to be actively involved in the supported work, rather than acting only as a funder. The specific forms of involvement would be defined in the full notice and the cooperative agreement terms.
7) How much funding was anticipated for Year 1?
For Year 1, CDC anticipated approximately $20,000,000 in total funding, subject to the availability of funds.
8) How many awards did CDC expect to make?
CDC expected to make 2 awards.
9) Why does the announcement list a Year 1 award ceiling of $0?
The posted Year 1 award ceiling being listed as $0 is noted as a signal that CDC is typically not setting a per-award maximum amount in the announcement, rather than indicating that there is no funding.
10) Who was eligible to apply?
The opportunity was open to unrestricted applicants, meaning any entity type could apply, subject to any additional eligibility clarifications included in the full notice.
11) What was the application deadline?
The posting indicates an original closing date of February 21, 2020, with electronic submissions due by 11:59 p.m. Eastern Time.
12) Is this opportunity focused on HIV only?
No. The opportunity is positioned to support HIV and TB epidemic control goals, with a digital and informatics focus that strengthens systems used by both HIV and TB programs.
13) Why are eHealth and digital health emphasized for HIV and TB programs?
Because HIV and TB programs generate large volumes of patient-level and site-level data that must be secure, timely, and usable for real-world decision-making. Without strong digital and informatics systems, it is difficult to track outcomes, identify gaps, and improve performance.
14) What are the main program areas supported by this opportunity?
The opportunity centers on four main areas: (1) interoperable health information systems (HIS); (2) country digital health strategies plus governance and policy; (3) indigenous health informatics capacity building; and (4) monitoring and evaluation (M and E) of HIS implementation.
15) What kinds of health information system (HIS) work are supported?
The opportunity supports the design, development, implementation, evaluation, and practical use of secure, standards-based, interoperable HIS.
16) What does "interoperable" mean in the context of this opportunity?
Interoperability refers to the ability of different health information systems to connect and exchange data in a standards-based way. The announcement highlights that countries often have disconnected systems across clinics, laboratories, pharmacies, and national reporting platforms, which makes it difficult to follow patients and measure outcomes.
17) Why are standards and interoperability highlighted so strongly?
Because disconnected systems create gaps in patient tracking from testing through treatment and outcomes (including viral suppression). Standards and interoperability help enable more complete patient histories and better reporting across the care continuum.
18) What is meant by "secure" systems in this announcement?
The description emphasizes that data must be secure and that governance and policy should address privacy and security. The goal is to protect sensitive patient and program information while still enabling timely use for decision-making.
19) What kinds of strategy and policy activities are included?
The opportunity supports the development, implementation, evaluation, and/or adoption of country eHealth or digital health strategies, along with governance and policy environments that make those strategies workable. This includes national rules and coordination mechanisms for system approvals, data sharing, privacy and security, technical standards, and alignment among stakeholders.
20) Why is governance a recurring theme?
Because governance affects how systems are approved, how data are shared, how privacy and security are handled, which technical standards are used, and how ministries, implementing partners, and donors coordinate investments to avoid duplicative systems.
21) What does the opportunity mean by "indigenous health informatics capacity"?
It means building local workforce and institutional capacity so that countries can maintain and improve their health information systems over time, reducing long-term dependence on external technical assistance.
22) What kinds of workforce skills are emphasized?
The announcement highlights developing in-country expertise in informatics leadership, system administration, data standards, interoperability architecture, analytics, and the operational realities of running digital systems in public health settings.
23) What is meant by monitoring and evaluation (M and E) of HIS implementation?
It means evaluating the implementation and functioning of the information systems themselves, not just HIV or TB health outcomes. The focus includes system use, data quality, interoperability performance, reporting timeliness, and whether systems support better program decisions and performance improvement.
24) How is HIS M and E different from standard HIV/TB program M and E?
Standard program M and E often focuses on health outcomes and service delivery results. HIS M and E, as described here, examines whether the digital systems enabling those results are operating as intended (for example, consistent facility use, better data quality, and improved timeliness and completeness of reporting).
25) What practical program use cases are mentioned?
The announcement notes use cases such as improving supply chain logistics (ensuring commodities and medications are available where needed), optimizing laboratory utilization (improving testing capacity and results reporting to support treatment decisions), and improving staffing allocation (using site-level program data to guide human resources for health decisions).
26) How does strengthening data flow help countries reach epidemic control goals?
By linking disparate systems and improving data flow, countries can track 95-95-95 progress more accurately, identify gaps by geography or population, improve decision-making with routine data, and strengthen sustainability of digital investments.
27) What problem is this opportunity trying to solve with "connected" systems?
It addresses the challenge of multiple disconnected systems across parts of the health sector (clinics, labs, pharmacies, national reporting), which can prevent reliable patient tracking, reduce data quality, and limit the ability to measure and improve performance.
28) Does the opportunity focus on sustaining prior investments?
Yes. A stated aim is to protect prior PEPFAR investments in digital infrastructure by ensuring systems are sustainable, secure, and fit for purpose.
29) What does "fit for purpose" imply here?
In the context provided, it implies digital systems should be practical and usable for real-world decision-making, support routine operations (like reporting and supply chain), and reliably enable tracking of program performance and outcomes.
30) Is the work described as country-level or headquarters-led?
The opportunity is described as supporting headquarters-led work under PEPFAR, while focusing on country digital health strategies, systems, governance, and workforce capacity that enable country programs to perform and report effectively.
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