Using Omics to Define Human Placental Development and Function Across Pregnancy (R01) | RFA HD 16 036

Opportunity Information: Apply for RFA HD 16 036

Using Omics to Define Human Placental Development and Function Across Pregnancy (R01) is a National Institutes of Health (NIH) funding opportunity that supports research aimed at building detailed, gestation-spanning omics profiles of the human placenta. The central scientific focus is to map how placental development and function change across pregnancy using modern high-throughput approaches (for example, genomics, transcriptomics, epigenomics, proteomics, metabolomics, and related multi-omics strategies). Projects supported under this announcement are expected to generate data that can clarify normal placental biology across gestational stages and help establish foundational reference information that the field can use to better understand placental health and disease.

A major emphasis of the opportunity is resource building for the broader research community, not just producing findings for a single lab or consortium. The FOA explicitly highlights the goal of creating a community resource made up of research resources, complex datasets, and associated metadata that are broadly available and shared. In practical terms, the expectation is that funded work will produce high-value, well-annotated omics datasets and supporting materials that other investigators can reuse, reanalyze, and integrate with their own studies. This resource-building goal is tied to the broader long-term vision of accelerating innovation in placental science, including providing a foundation for integration with emerging technologies that aim to enable safe, real-time assessment of placental status in vivo during pregnancy.

The mechanism is an R01 research project grant, and the opportunity is categorized as a discretionary grant within the Health, Income Security and Social Services activity area (CFDA 93.865). The funding opportunity number is RFA-HD-16-036, with an award ceiling listed at $500,000. The original closing date shown in the source information is December 18, 2015, and the creation date is September 17, 2015, indicating this is a specific historical announcement rather than an open-ended program description.

Eligibility is broad and includes many types of domestic U.S. applicants as well as certain international entities. Eligible applicants include state, county, city/township, and special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments; Native American tribal organizations (other than federally recognized tribal governments); public housing authorities and Indian housing authorities; nonprofits with and without 501(c)(3) status (outside of higher education); for-profit organizations other than small businesses; small businesses; and other eligible entities. The FOA also calls out additional eligible applicants such as Alaska Native and Native Hawaiian Serving Institutions; Asian American Native American Pacific Islander Serving Institutions (AANAPISIs); Hispanic-serving Institutions; Historically Black Colleges and Universities (HBCUs); Tribally Controlled Colleges and Universities (TCCUs); faith-based or community-based organizations; regional organizations; U.S. territories or possessions; and non-U.S. (foreign) organizations, along with Indian/Native American tribal governments that are not federally recognized.

Overall, this grant opportunity is designed for teams that can combine rigorous placental biology with strong omics and data-generation capabilities, along with a clear plan for producing standardized, well-documented, shareable datasets that can function as a lasting community resource. The intent is to push the field toward comprehensive, integrative views of placental development across gestation while simultaneously enabling downstream advances, including the development and validation of next-generation tools for monitoring placental function during pregnancy.

• The National Institutes of Health in the health, income security and social services sector is offering a public funding opportunity titled "Using Omics to Define Human Placental Development and Function Across Pregnancy (R01)" and is now available to receive applicants.
• Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.865.
• This funding opportunity was created on 2015-09-17.
• Applicants must submit their applications by 2015-12-18. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
• Each selected applicant is eligible to receive up to $500,000.00 in funding.
• Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501 (c) (3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501 (c) (3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For-profit organizations other than small businesses, Small businesses, Others.

Apply for RFA HD 16 036

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