Opportunity Information: Apply for RFA CK 17 001

The grant opportunity titled "Creation of a Healthcare-Associated Infectious Disease Modeling Network to Improve Prevention Research and Healthcare Delivery" (Funding Opportunity Number: RFA CK 17 001) is a CDC-led effort under the U.S. Department of Health and Human Services to strengthen the nation s ability to understand and reduce healthcare-associated infections (HAIs), with a major emphasis on infections caused by antimicrobial resistant organisms. The central goal is to fund innovative transmission modeling research that can explain how HAIs spread within and across healthcare settings and to turn that improved understanding into practical tools and strategies that help healthcare systems prepare for, detect, control, and prevent these infections. Rather than focusing on a single disease or one facility type, the opportunity is designed to build broader modeling capacity and usable insights that can improve infection prevention research and ultimately support safer healthcare delivery.

A key feature of this announcement is the creation of a new modeling network made up of multidisciplinary scientists who use computational and mathematical approaches. In practice, that means the funded teams are expected to bring together expertise that might include infectious disease epidemiology, biostatistics, mathematics, computer science, health services research, clinical infection prevention, and related areas. The work is centered on transmission modeling, which can include building and refining models that represent how pathogens move through patient populations, healthcare workers, wards, facilities, and connected health systems, and how those dynamics change under different prevention and control measures. The modeling focus is explicitly tied to real-world prevention problems, especially those involving antimicrobial resistance, where delayed detection, complex care pathways, and interconnected facilities can allow resistant pathogens to persist and spread.

The funding mechanism is a cooperative agreement, which generally signals substantial involvement from the CDC during the project period. While the announcement text provided does not list specific required activities, this type of mechanism usually implies active collaboration, coordination, and shared priorities between awardees and the agency, particularly important here because the aim is not only to support separate modeling projects but also to build a coordinated network. The intended outcome is a stronger national research and response capability that can generate models and tools relevant to decision-making in healthcare infection prevention and control.

From an administrative standpoint, this is a discretionary grant categorized under Health, with CFDA number 93.084. Applications were created in the CDC ERA system, with an opportunity creation date of October 21, 2016 and an original closing date of January 31, 2017, with electronic submissions due by 5:00 p.m. Eastern Time on the deadline. The award ceiling is listed at 650,000, and the CDC anticipated making about five awards, suggesting a small number of relatively substantial projects intended to serve as the initial core of the national modeling network.

Eligibility is broad and spans many sectors, reflecting the multidisciplinary and applied nature of modeling for HAIs. Eligible applicants include state, county, and local governments; special district governments; independent school districts; public and state-controlled institutions of higher education; private institutions of higher education; federally recognized Native American tribal governments and other tribal organizations; public housing authorities and Indian housing authorities; nonprofit organizations with or without 501(c)(3) status (excluding higher education institutions when specified); for-profit organizations other than small businesses; and small businesses. This wide eligibility pool indicates the CDC is open to proposals from academic groups, public health agencies, healthcare research organizations, and private-sector teams capable of rigorous modeling work, as long as they can contribute meaningfully to the overall network and the prevention mission.

Overall, this opportunity is best understood as an investment in modeling infrastructure and applied research capacity for HAIs, particularly antimicrobial resistant threats. By funding a network rather than isolated projects, the CDC is signaling that progress in this area requires shared methods, coordinated learning, and tools that can be compared, validated, and used across settings. The emphasis on preparedness, detection, control, and prevention frames modeling not as an academic exercise but as a practical engine for improving infection prevention policies and operational decisions in U.S. healthcare environments.

  • The Department of Health and Human Services, Centers for Disease Control and Prevention - ERA in the health sector is offering a public funding opportunity titled "Creation of a Healthcare-Associated Infectious Disease Modeling Network to Improve Prevention Research and Healthcare Delivery" and is now available to receive applicants.
  • Interested and eligible applicants and submit their applications by referencing the CFDA number(s): 93.084.
  • This funding opportunity was created on Oct 21, 2016.
  • Applicants must submit their applications by Jan 31, 2017 Electronically submitted applications must be submitted no later than 500 p.m., ET, on the listed application due date.. (Agency may still review applications by suitable applicants for the remaining/unused allocated funding in 2026.)
  • Each selected applicant is eligible to receive up to $650,000.00 in funding.
  • The number of recipients for this funding is limited to 5 candidate(s).
  • Eligible applicants include: State governments, County governments, City or township governments, Special district governments, Independent school districts, Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Private institutions of higher education, For profit organizations other than small businesses, Small businesses.
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